ABSTRACT
Background: gastroesophageal reflux disease [GERD] ranks as one of the most common gastrointestinal disorders. Up to this date, no studies examined the level of health knowledge of Saudi population about GERD
Aim of the study: this study aimed to assess knowledge about GERD signs, symptoms and risk factors in Saudi residents of Altaif City
Methods: this minimal knowledge questionnaire that was distributed among the general public in Altaif City, Saudi Arabia. The questionnaire consisted of two sections: section 1 included personal data and section 2 explored the awareness and knowledge about the most common symptoms and risk factors of GERD. Only questionnaires without missing data were subjected to statistical analysis
Results: respondents who answered all the questions correctly represented 7.4%, while those who answered all wrongly were 1.5%. The mean proportion of minimal medical knowledge [MMK] score was 64.66%. Respondents with higher education [p < 0.001], medical background [p = 0.004] and health knowledge derived from books [p = 0.001] achieved the highest total scores. Sex, residence, marital status, and past/family history of GERD seemed not to affect the mean MMK scores [p = 0.277, 0.234, 0.970, 0.873 and 0.085 respectively]
Conclusion: some symptoms [Globus sensation, dysphagia and odynophagia] and risk factors [Scleroderma and asthma] for GERD remained unknown to nearly half the participants. We recommend providing health information concerning GERD on the Internet or to prepare booklets to be distributed through the health care facilities
ABSTRACT
Background: noise is the most stressful factor for experimental animals. So these studies aim to clarify its effect on some physiological and histological parameters
Material and methods: 36 Female rats were divided into four groups [6/each]:1-control, 2-treated with sulpiride drug, 3- noise exposure [90db/3h per day for 30days], 4-noise + drug
Results: drug recorded no significant change in all the studied parameters. Noise stress recorded a significant increase in creatinine, total lipids, TG, Cholesterol, HDL-C, LDL-C and no significant changes in urea, uric acide. It has been detected that sulpiride drug ameliorated most of these parameters.Concerning the histological and histochemical studies sulpiride treatment showed no detectable changes in the kidney tissue with exception of increased lymphocytes. Exposure to noise showed many dystrophic changes in the kidney tissue, but drug treatment improved all the previous changes and this indicates the protective effect of sulpiride against noise exposure
Conclusion: it is useful to use sulpiride drug in people who exposed to noise stress
ABSTRACT
Background: noise is the most stressful factor and human being. So these studies aim to clarify its effect on some physiological and histological parameters
Material and methods: 24 Female rats were divided into four groups [6/each]:1-control, 2-treated with sulpiride drug, 3- noise exposure [90db/3h per day for 30days], 4-noise + drug
Results: drug recorded a significant increase only in the percentage of body weight gain but the other parameters showed no significant changes. Noise stress recorded a significant increase in glucose, ALT, GGT, TP, globulin. A significant decrease in percentage of body weight gain and A/G ratio were also detected . It has been detected that Sulpiride drug ameliorated most of these parameters. Concerning the histological and histochemical studies sulpiride treatment showed no detectable changes in the liver tissues with exception of increased lymphocytes. Exposure to noise showed many dystrophic change in tissue, but drug treatment improved all the previous changes and this indicates the protective effect of sulpiride against noise exposure
Conclusion: it is useful to use sulpiride drug in people who expose to noise stress